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BIO2217 Transfusion Science

Semester 2, 2022 Toowoomba On-campus
Units : 1
Faculty or Section : Faculty of Health, Engineering and Sciences
School or Department : School of Health and Medical Sciences
Grading basis : Graded
Course fee schedule : /current-students/administration/fees/fee-schedules

Staffing

Examiner:

Requisites

Pre-requisite: BIO1103 and BIO1104 and BIO2108

Overview

Transfusion Science is a specialised sub-discipline of Haematology focussed on the provision of safe, viable and compatible blood products for patients requiring transfusion. This course will provide students with the theory and practical skills required by health practitioners working in transfusion laboratories and blood banks. This course will also provide students with a comprehensive understanding of the therapeutic use of blood products in the clinical setting and foster a well-informed systematic approach to the performance of the relevant laboratory investigations.

As part of the USQ accreditation agreement with the Australian Institute of Medical and Clinical Scientists (AIMS), students are required to attempt and submit all assessment items in this course. Students are also required to obtain at least 80% of the marks allocated to the practical/laboratory skills assessment in this course.

This course builds on the introduction to Transfusion Science presented in BIO1103 Pathology Studies and the introduction to erythrocyte membranes and red blood cell antigens presented in BIO2108 Haematology 1. Transfusion Science will provide students with a solid understanding of the theory and practice of pre-transfusion testing and the procedures involved in the provision of compatible blood products for patients requiring transfusion of red blood cells, platelets and fresh and fractionated plasma products. This course also explores the pathogenesis and associated laboratory investigation of haemolytic transfusion reactions, haemolytic disease of the foetus and newborn and other serious hazards of transfusion. The isolation, assessment, storage and use of haemopoietic stem cells in transplantation procedures is also explored. The course is designed to enable graduates to commence work in a transfusion laboratory.

The residential school component of this course will provide students with the opportunity to perform a complete pre-transfusion work-up including ABO and Rh(D) blood typing, antibody screening, antibody identification, red blood cell phenotyping and cross-matching. The residential school and associated skills evaluation will enhance the student's capacity and confidence to make critical and informed judgements in a professional setting.

This course contains a mandatory residential school for both external and on-campus students.

Course learning outcomes

On completion of this course students will be able to:

  1. describe the nature of the antigens and antibodies of the ABO and Rhesus blood group systems, explain the clinical significance of the major blood group systems in transfusion medicine and demonstrate a deep understanding of ABO and Rh(D) compatibility;
  2. explain the theory of the various laboratory procedures involved in pre-transfusion testing including ABO and Rh(D) blood grouping, antibody screening, antibody identification, red blood phenotyping and cross-matching;
  3. select and perform the appropriate laboratory procedures required for the provision of compatible red blood cells for transfusion;
  4. describe the pathogenesis and laboratory investigation of autoimmune haemolytic anaemia, haemolytic transfusion reactions and haemolytic disease of the foetus and newborn and demonstrate an understanding of the appropriate use of fresh and fractionated blood products in the management of various haematological disorders;
  5. define haemovigilance and patient blood management, discuss the management of blood product inventories, and explain the quality control and quality assurance procedures required for the efficient operation of a hospital blood bank;
  6. investigate relevant literature and demonstrate a high level of academic, scientific and professional literacy;
  7. demonstrate safe work practices and a clear understanding of the ethical and professional responsibilities associated with working in a transfusion laboratory;

Topics

Description Weighting(%)
1. Introduction to the theory and practice of immunohaematology 12.00
2. The ABO and Rhesus Blood group systems 20.00
3. ABO subgroups and ABO blood group discrepancies and other clinically significant blood group systems 12.00
4. Pre-transfusion testing 20.00
5. Blood and blood products 12.00
6. Haemopoietic stem cell transplantation 12.00
7. Serious hazards of transfusion 12.00

Text and materials required to be purchased or accessed

Johns, G, Gockel-Blessing, E, Zundel, W & Denesiuk, L 2015, Clinical Laboratory Blood Banking and Transfusion Medicine, Principles and Practice, Pearson Clinical Laboratory Science Series, Pearson Education Inc.
(ISBN. 13-978-0-13-083331-0.)

Student workload expectations

To do well in this subject, students are expected to commit approximately 10 hours per week including class contact hours, independent study, and all assessment tasks. If you are undertaking additional activities, which may include placements and residential schools, the weekly workload hours may vary.

Assessment details

Approach Type Description Group
Assessment
Weighting (%)
Assignments Written Quiz No 20
Assignments Written Essay No 20
Assignments Practical Practical No 20
Examinations Non-invigilated Time limited online examinatn No 40
Date printed 10 February 2023